Rescue DirectorySouth Carolina Animal Rescue & Sanctuary Directory
Find dog and cat rescues, equine and farm animal rescues, wildlife organizations, and sanctuaries serving South Carolina.
Browse by the animals an organization helps or the care it provides. Each listing includes its location, focus, services, and official website so you can learn more about adopting, fostering, volunteering, or supporting its work.An organization may appear in more than one category when its programs overlap. Animal shelters are listed separately in our Animal Shelter Directory.
Dog Rescues
Organizations rescuing, rehabilitating, and rehoming dogs through foster care, veterinary treatment, and adoption programs.
Care models and verified no-kill policies are noted in individual listings.
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Location: Florence County, South Carolina — Rescue Campus; also operates in the Washington, D.C. area
Category: Dog Rescues · Cat Rescues
Care model: Rescue campus, transport, and foster-based adoption
Focus: At-risk shelter animals · Medical care · Foster placement · AdoptionLucky Dog Animal Rescue helps dogs and cats facing euthanasia in shelters. Its South Carolina Rescue Campus supports intake, medical care, and stabilization before animals move into foster homes and adoption programs.
Care includes vaccinations, treatment, and surgery when needed. The organization also promotes spay/neuter and responsible pet ownership through community education.
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Location: West Columbia, South Carolina
Category: Dog Rescues · Cat Rescues
Focus: Homeless dogs and cats · Rehabilitation · Adoption · Veterinary accessPETSinc rescues and cares for homeless dogs and cats, providing medical, nutritional, and behavioral support while preparing them for adoption.
Its services include a low-cost veterinary clinic and spay/neuter surgery. Community education encourages responsible pet care and helps address pet overpopulation.
Cat Rescues
Organizations rescuing, caring for, and rehoming cats through foster care, veterinary treatment, and adoption. Some also provide Trap-Neuter-Return (TNR) support for community cats.
Care models and verified no-kill policies are noted in individual listings.
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Location: Florence County, South Carolina — Rescue Campus; also operates in the Washington, D.C. area
Category: Dog Rescues · Cat Rescues
Care model: Rescue campus, transport, and foster-based adoption
Focus: At-risk shelter animals · Medical care · Foster placement · AdoptionLucky Dog Animal Rescue helps dogs and cats facing euthanasia in shelters. Its South Carolina Rescue Campus supports intake, medical care, and stabilization before animals move into foster homes and adoption programs.
Care includes vaccinations, treatment, and surgery when needed. The organization also promotes spay/neuter and responsible pet ownership through community education.
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Location: West Columbia, South Carolina
Category: Dog Rescues · Cat Rescues
Focus: Homeless dogs and cats · Rehabilitation · Adoption · Veterinary accessPETSinc rescues and cares for homeless dogs and cats, providing medical, nutritional, and behavioral support while preparing them for adoption.
Its services include a low-cost veterinary clinic and spay/neuter surgery. Community education encourages responsible pet care and helps address pet overpopulation.
Equine & Farm Animal Rescues
Organizations rescuing horses, donkeys, and other farm animals from neglect, abandonment, and unsafe situations. Services may include medical care, rehabilitation, responsible adoption, and permanent sanctuary.
Listings identify whether the organization offers adoption, lifelong care, or both.
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We haven’t added an organization to this category in South Carolina yet. Listings will be added as we identify and review relevant rescues or sanctuaries.
Sanctuaries & Lifetime Care
Organizations providing permanent care for animals who need lifelong protection, including seniors and animals with medical, behavioral, or trauma-related needs.
Some also offer adoption or forever foster programs for suitable animals.
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Location: South Carolina
Category: Wildlife & Nature Conservation · Sanctuaries & Lifetime Care
Care model: Wildlife rehabilitation and release, with permanent care for non-releasable deer
Focus: Orphaned whitetail fawns · Injured and sick deer · Rehabilitation · Lifelong careHickory Haven Fawn Rescue cares for orphaned, sick, and injured whitetail fawns, working toward release when appropriate. Non-releasable captive deer receive lifelong sanctuary care.
The organization also educates the public about wildlife laws and responsible intervention. Deer sponsorships help fund food, medical care, and habitat needs.
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Location: Bishopville, South Carolina
Category: Sanctuaries & Lifetime Care
Care model: Rabbit rescue, rehabilitation, and adoption
Focus: Abandoned and surrendered rabbits · Neglect cases · Veterinary care · Rabbit welfare educationPaisley’s Bunny Rescue provides refuge and veterinary care for rabbits affected by abandonment, abuse, and unsafe conditions. Its work includes rehabilitation, adoption, and education about rabbits’ needs as companion animals.
The organization encourages informed, lasting commitments to rabbit care.
Wildlife & Nature Conservation
Organizations supporting wildlife through rescue, rehabilitation, public education, habitat protection, or species conservation.
Services vary. Listings distinguish wildlife rehabilitation and release from permanent care and conservation work.
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Location: South Carolina
Category: Wildlife & Nature Conservation · Sanctuaries & Lifetime Care
Care model: Wildlife rehabilitation and release, with permanent care for non-releasable deer
Focus: Orphaned whitetail fawns · Injured and sick deer · Rehabilitation · Lifelong careHickory Haven Fawn Rescue cares for orphaned, sick, and injured whitetail fawns, working toward release when appropriate. Non-releasable captive deer receive lifelong sanctuary care.
The organization also educates the public about wildlife laws and responsible intervention. Deer sponsorships help fund food, medical care, and habitat needs.
Before contacting an organization
Adoption requirements, service areas, and intake availability vary. Please contact the organization directly to confirm its current programs and whether it can help with your situation.